Breakthrough:  WVU Rockefeller Neuroscience team first to use ultrasound to treat Alzheimer's

Nov 20, 2019 3:09 PM

doihearanamen

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The procedure in West Virginia involved the use of ultrasound waves focused through a specialized helmet with more than 1,000 probes targeting a precise spot in the brain, coupled with microscopic bubbles.
The reaction opens up the brain-blood barrier — a nearly impenetrable shield between the brain’s blood vessels and cells that make up brain tissue.
In this case, the West Virginia team targeted the hippocampus and the memory and cognitive centers of the brain that are impacted by plaques found in patients with Alzheimer’s.

Link to full article: https://www.wvnews.com/news/wvnews/historic-breakthrough-wvu-rockefeller-neuroscience-team-first-to-use-ultrasound/article_cfe6fefc-eee9-5add-b853-23642a0a91a7.html

FP Edit: Way to promote science, guys!

I visited my grandma on Christmas. She thought i was a robber & hysterically cried until i left. i cried myself all day. F- alzheimer's

6 years ago | Likes 8 Dislikes 0

This gets me excited that we might see an actual treatment for Alzheimer's one day. Next step is a cure!

6 years ago | Likes 128 Dislikes 4

What were the results of the treatment?

6 years ago | Likes 2 Dislikes 0

Terrible disease that truly destroys a human beings mind and soul. Good on them.

6 years ago | Likes 5 Dislikes 0

fucking amazing!!!!!

6 years ago | Likes 2 Dislikes 0

And if this is the cure, let’s hope it’s affordable too.

6 years ago | Likes 2 Dislikes 0

Seems a bit like advanced ECT, but I admit I'm going in at face value before reading in full.

6 years ago | Likes 2 Dislikes 0

Annnd? The story ends too soon.

6 years ago | Likes 8 Dislikes 0

No, it's just that's all there is to report right now. This is step 1 of a potential series of 100 steps to actual treatment.

6 years ago | Likes 4 Dislikes 0

451: Unavailable due to legal reasons. That means the site's scamming you for your data.

6 years ago | Likes 3 Dislikes 0

My fave part is where the article doesn't state what the treatment is actually meant to achieve beyond 'opening the blood-brain barrier'.

6 years ago | Likes 32 Dislikes 1

I think the idea is so you can get larger molecule drugs into the brain.

6 years ago | Likes 5 Dislikes 0

Agreed, that's the most important part. I imagine it was to allow drug delivery.

6 years ago | Likes 5 Dislikes 0

yes it does - could be clearer. “Plaques [ ] block-up the brain’s connectivity,” ... "these plaques are cleared with ultrasound technology"

6 years ago | Likes 2 Dislikes 0

Mom has it. She is under 60.

6 years ago | Likes 2 Dislikes 0

My dad died at 63 from Early Onset a few years ago. It fucking sucks.

6 years ago | Likes 1 Dislikes 0

Fuck Alzheimer's

6 years ago | Likes 2 Dislikes 0

I'm sorry- You have Alzheimer's and cancer. Well- at least I don't have cancer.

6 years ago | Likes 2 Dislikes 0

Hey this article is security blocked in EU.

6 years ago | Likes 2 Dislikes 0

And then insurance companies will charge $150,000 per treatment

6 years ago | Likes 9 Dislikes 1

The research into that particular treatment method likely cost hundreds of millions to get to this point. Billions of you total all the

6 years ago | Likes 2 Dislikes 2

Failures that ruled out methods and drugs.

6 years ago | Likes 2 Dislikes 2

Let's Gooooo Mountaineers! Proud of my Alma Mater!

6 years ago | Likes 9 Dislikes 1

Go 'eers!

6 years ago | Likes 2 Dislikes 0

Horrible disease! Had a dear friend commit suicide when diagnosed. Gave me a nice pocket knife a week before he did it. Didn’t dawn on me!

6 years ago | Likes 4 Dislikes 0

FINALLY! ONE OF THE FUCKING AMAZING TREATMENTS I HEAR ABOUT IN SCIENCE ARTICLES ACTUALLY GETS IMPLEMENTED.

6 years ago | Likes 2 Dislikes 0

Good God, they discovered dr Rife!

6 years ago | Likes 3 Dislikes 0

Don’t avoid eating olive oil and animal fat like fish or shrimp. Unfortunately this generation avoided fat thinking it made them fat. 1/2

6 years ago | Likes 3 Dislikes 0

Low fat diets are associated with neurological issues. I don’t think we’ll see as much of this disease in the future. 2/

6 years ago | Likes 1 Dislikes 0

This is awesome and all but this article is over a year old.

6 years ago | Likes 5 Dislikes 0

And it's not treatment, it's a method of access for potential treatment. Nobody fucking reads.

6 years ago | Likes 4 Dislikes 0

Didnt they do this on Grey's Anatomy?

6 years ago | Likes 2 Dislikes 0

I don't want a news publication about it, I want a documentary about it!!

6 years ago | Likes 2 Dislikes 0

Great. This is so encouraging

6 years ago | Likes 3 Dislikes 0

My dad is losing a battle to it now. I miss my dad even though he stands there in front of me. He struggles to remember me sometimes.

6 years ago | Likes 2 Dislikes 0

Thanks to Science, Researchers, folks who worked Uber hard to get to their scientific/technical roles, University of WV and trial patients

6 years ago | Likes 2 Dislikes 0

Note: fictional overlords NOT included

6 years ago | Likes 1 Dislikes 0

WVnews blocks EU, so here: https://medium.com/@FUSFoundation/emerging-applications-of-focused-ultrasound-alzheimers-disease-c34e9d0273cf

6 years ago | Likes 4 Dislikes 0

In a misguided implementation of GDPR - which makes me wonder what they would do to my personal data if they had it!

6 years ago | Likes 5 Dislikes 0

Neuroscience researcher here. Bad and good news. Bad is that unless there is some treatment that they don't describe/I missed, this (1/?)

6 years ago | Likes 4 Dislikes 0

is a delivery method, not a treatment. One big issue to treating issues in the brain is that it is difficult to deliver drugs across (2/?)

6 years ago | Likes 7 Dislikes 0

*treating diseases Sorry, I'm highly caffeinated and typing this on my phone.

6 years ago | Likes 1 Dislikes 0

the blood-brain barrier (BBB). This treatment opens it up enough that we can deliver drugs and other substances through it. So this (3/?)

6 years ago | Likes 7 Dislikes 0

is not a way to treat Alzheimers. But it is a way to deliver things that will treat it (which we're still developing). The good news: (4/?)

6 years ago | Likes 6 Dislikes 0

not only can we use this to deliver medicine for Alzheimers, we can use it to deliver medicine for any disease of the brain. A couple (5/?)

6 years ago | Likes 4 Dislikes 0

of the articles I skimmed discussed its use in treating brain tumors as well. So to sum up, this article is sensationalized, but this (6/7)

6 years ago | Likes 4 Dislikes 0

Hello fellow researcher, the good news is that the ultrasound vibrations may be the treatment (1/2)

6 years ago | Likes 2 Dislikes 0

Well they may have some effect, but that's not what the article you linked talked about. It was talking about stim at 80 HZ, which...

6 years ago | Likes 2 Dislikes 0

amplifies/mimics naturally occurring gamma oscillations in the brain. The ultrasound used in this treatment is at least 2,000 Hz. Probably..

6 years ago | Likes 2 Dislikes 0

closer to 2,000,000 Hz. So it affects the treated tissues through direct physical contact, rather than interacting with systemic...

6 years ago | Likes 2 Dislikes 0

electric oscilatrions.

6 years ago | Likes 2 Dislikes 0