Jun 20, 2015 2:42 PM
floppydonkeydank
308140
8142
138
cupcaker
To be fair, I don't remember anyone in Jurassic Park having cancer... so maybe they did cure it.
johanevj
No. It doesn't mean that.
SnakeskinJacket
We're going to be seeing if we have the same priorities sooner than you think - https://en.m.wikipedia.org/wiki/Crispr
MonserrSans2
But the electron is being hit with a photon regardless of where the photon goes afterwards, be it an eye ball or a pile a crap.
Julios
The good stuff haha. That is why bad guys are bad.
roeloel
+1 i agree with his argument
HalfApeHalfBanana
Also its a goddamn film
Treblaine
Cancer-cure is almost the opposite of cloning. Curing cancer is getting certain cells to stop living, cloning is about making them live anew
kongfuchicken
Heh... On the fly! Get it?
PattiMichelle
But that's a useless answer, right? The actuality is that these are all inventions, so nobody has any idea what people would do there.
FlareonTheFalseProphet
In the Marvel universe Venom showed the capability to cure cancer if it bonded with the person who had it
Elerich
https://imgflip.com/i/n6zjc
bjjohnson6021
How they gonna cure cancer when they can't even think to add another tower to the island so their radios and phones work.
AClassyWalrus
BUT MOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOMMMMMMM!!! I WANNA MAKE DINOSAURS!!!!!
Digiphage
Some people take FICTION way too seriously...
CaiGwydion
They certainly can do. It's gets ridiculous sometimes. It's a movie. Oh well, some people will find something to complain about.
Stegostoma
Notice how they fuck shit up? Clearly they don't know as much as they pretend.
aestheticwolfgang
Jurassic exists inside a post-classical hollywood state, therefore it operates outside of our world within in its own bubble universe
FrankCastlePunisher
The solution to this debate would be to turn everybody who has cancer into dinosaurs...win win?
Chizbits
Pterodactyls always make me think of Beetlejuice when they change their faces to scary.
BiologyNStuff
You don't need mastery of the entire genome to clone and/or change an organism.
Also, cancer is a way more complicated problem than just genomics.
Spanked84
Comic panel is from Spider-man and X-men if anyone cares. Issue #2 I believe.
Alicecold
I need to point out that your link is very meta.
My link?
the autolink #2
Ohhh lol
thisisjoey
I always wondered why they keep thinking it's a good idea. "Sure lots of people died the last 3 times, what could possibly go wrong now"
I loved the movie though, just saw it tonight, it was great
Magnivore
Is that pterodactyl wearing underwear?
elandriel
read the books, it actually talks about how Hammond was really arrogant with his technology that all he really wanted to do was (1/2)
elitehunter67
I agree in the sense that he was arrogant. But most of Crichtons books have to do with abuse of power. People are douchbags. Not science.
make money, even though he could have done a lot of scientific good with it. He was a dick. (2/2)
jetflight
This. Read a book, people.
TheresAGermanWordForThat
Common thing for supervillains
ToastedVanilla
Excuses excuses. Money is a way to a mean. Just ask Lex Luthor. A supervillian advertising hair growth products does sound incredible though
JamBarn
Sauron does what he wants, spider-man. Don't try to impose your values.
thatpatguy
So, uh... how often do we see people with cancer in the Jurassic Park movies?
how often do we see dinosaurs in cancer movies?
GlitterInTheDarkNearTheTannhauserGate
None! Cancer cure made them enough money to finish the park
MartialSpork
I'm upvoting you solely because C-beams glitter in the dark near the Tannhauser Gate
thanks, but i am afraid in time it'll be lost, like tears in rain
ImASexyUnicorn
And why they spared no expense!
JauneArcMKII
I'm fairly sure the human genome and dino genomes aren't the same, though. I'm also not a scientist, so I know fuck all.
CaptainAmerica24
yes the genomes aren't the same, but basic DNA composition should be. If you can manipulate Dino genes, you should be able to do so with ppl
zviosif
Actually, they are EXACTLY the same. TMYK.
veritas1980
1 minute internet research indicates an estimate of 65%
ScruffyBelievesInThisCompany
I thought everyone on this site was a scientist!
probably a lot more similar than you think.
bananamannock
Legit geneticist here. We don't need to know a genome to clone it...
NB. Messing with genome in humans is illegal in most countries if ur referring to genetic mods.
nopo
When you are at the point where you can do large scale genetic engineering and splicing, the differences stop mattering as much.
cerberus63
DNA is DNA is DNA. A lot of our genetic research happens using flies and the like. Genes do the same stuff to them that it does to us.
That being said Jurassic Park totally uses it as a vague hand wave to explain any techno-sorcery that is happening.
JrElmoe
Nothing really related to the genomes, but more on the fact they can reconstruct the cell structures from the bottom.
Tunisia
I am a scientist and would like to state that actually, the human and tyrannosaurus genomes are identical.
Majorgrunt
well. A lot of it probably is.
MrPredator
The only thing I've learned is that rapid mutation of the human body would result in the death of the subject. On the otherhand... "science"
RhealityBytes
We would share a crazy amount of our DNA with random shit, like Bananas we share 50% of our DNA with them.
goldengoldblum
[Eugene I'm not actually a scientist gif]
whalekaraokeparty
We're all scientists here on imgur
TheGingerBeardedBiologist
They are very different. Also, being able to spice and replicate dino DNA doesn't mean we could cure diseases, especially ones like cancer.
BtchMuffin
Tell me, what kind of spice goes well with dino DNA?
longdarkteatimeofthesoul
1) But it would advance the hell out of gene therapy. The genomes are different but many of the basic mechanisms are the same. That's why we
I totally agree, there are many similarities too. I meant that tumblr OP is overgeneralising, and it's not as simple.
3) not always that simple).
2) can get E. coli to produce things like human insulin - the basic idea of DNA->RNA->Protein is the same in all organisms (although it's
bimpnottin
Thanks for giving a realistic view on the matter.
People often hate me for being a killjoy with these things. I still appreciate the humour, but also find it interesting to discuss it.
GreatWhiteSnark
You can make goats produce spider silk pretty easily so who fucking knows
vindik8or
You can make them produce the silk protein, but they can't spin it into silk.
MyxlPlyxl
Did somebody recently watch Game Theory? :3
DiplMaleNurseToBe
This is trivial, because the spider-silk genes are well known, so are the milk-producing promoters.
Not really, if the knowledge is the only barrier then does it matter what is turned into dinosaurs? Recently trex cells were found
Source Steve Irwin's son
Point is that you only have to put one gene at one point in a genome to get spiders milk. A living creature needs 1000 act genes in concert.
Wait. That's the problem? Not the fact that people's already well established cells and bone structure would have to be magically changed?
No, but the knowledge and the techniques to manipulate them are identical. Making a Tyrannosaurus rex from pieces is VERY advanced gentech.
underlord2132
But it implies a level of science high enough to do some cool shit. Other than dinosaurs that is.
amglasgow
No, but JP universe clearly has genetic technology in advance of ours, so probably there is better genetic therapy for cancer.
exacerangutan
Considering how well the dinosaur-making turns out do you REALLY thing they're ready for clinical trials?
Their dinosaurs turned out wonderfully -- it's not the fault of the geneticists their engineers designed the parks with no safety measures.
I'm just saying, you cure someone's cancer and next thing you know the cancer gets loose and starts eating people.
brotasticbrojaculation
can't fuck with that logic.
Cheesecakecrush
Maybe it IS cured in the JP universe, therefore people being eaten by dinosaurs don't give a flying fuck about cancer.
IAmDrBanner
Maybe it does, but it isn't the focal point of the movie, so really, why would they mention it at all? I don't understand the point of this.
I don't see any reason they would either. I was just answering the previous comment.
DarthFutuza
It would be a complete waste of screen time to have some side character be like, "Thank goodness we don't have to worry about cancer."
perpetuallylove
It's cuz we're fun at parties (in Chandler voice)
efemral
George W signed an executive order that effectively held back this kind of research for a decade.
Luciferyourgod
Link?
https://embryo.asu.edu/pages/george-w-bush-executive-order-13455-june-2007
VaclavUrbanek
Isn't one of Spider-Man's enemies literally a guy who wanted to cure himself with lizard DNA but instead mutated into a raging monster?
EmpoleonNorton
Yeah, was trying to regrow his lost arm. Curt Connors/The Lizard.
LamStock
Spidermans in the above picture.
Yes, that was my point. :)
The morale of the story is science is bad.
crookednixon
Basically this: http://dresdencodak.com/2009/09/22/caveman-science-fiction/
Sometimes I feel like lots of movies have that moral. Which is a little sad.
cegimerhange
I think the moral is more like "Don't be reckless" instead of "science is bad" in most cases.
GaryFreakinOak
The moral of the story is to never use experimental science on people, even if they volunteer. Or its you.
Stop cancer research today! It could result in zombie viruses!
SonOfTheShire
Ah, but Spider-Man also got his powers from science, and he's a good guy. Where's your moral now, Aesop?!
Spider-Man did not try to get spider powers, it was an accident. The Lizard tried to "play god" and it backfired.
Spider-man is a tragic hero, everyone he loves dies. His misfortune comes because of science's mistakes. Parents were murdered 4 science.
xrufus7x
But, because of science he is able to save countless lives, not only because of his powers, but also because he is a scientist himself. 1/2
Seems like the true moral is "With great power comes great responsibility"
Pssshhhh don't take jokes too seriously.
nerdextreme
Well 1 you cant cure cancer. There are all types of cancer that need different cures. 2 DNA splicing isn't (relatively) that hard.
GeneticGenius
this guy
bigbrother
Different cures 120% of the time. The protein that went awry is the primary target for the 'cure'/treatment and it doesn't always work.
Gene therapy delivered via virus is already curing cancer and it's still early stage. Very exciting. http://killingcancer.vice.com
DoctorWatchamacallit
*treating certain types of cancer under controlled conditions. that's hugely different from a cancer miracle cure
Agreed, check out the documentary. I think you'll be encouraged and it's very interesting.
I think one of the next stages will be altering epigenetic patterns to cure cancer. I love that field of genetics.
mybrothersmario
seriously, we can do that now, you just need to be able to fund it, and have the equipment.
and have dino DNA, which is basically gone by now. But we can try doing what they did in World and use other animal dna to get close
PGTipsMonkeh
Actually, blood vessels were found in a fossil back in 2003. One of the bones broke when it was transported, they looked closer, and voila!
:0
metalman125
Game theory? Game theory.
Doesn't mean all the DNA is intact. It's relatively stable but not millions of years stable. They can get fragments but more is unlikely.
SleepyWalrus
indeed, i read recently that they had found soft tissue in the marrow or so of a bone? maybe it's the same, but it's interesting nonetheless
Maybe not, but it certainly gives me hope. Always wanted a pet triceratops
Splicing DNA isn't hard; splicing the right DNA to do what you want is hard.
Genuinely, it's easy to accidentally clone your chair as some DNA in the wood of the chair you were sitting on ended up in PCR machine.
roight
rrrrrrrrooiiiiiiiiiiiiiiiiiiiiiiiiggggghhht...
IHateTheLetterF
We just need a machine that splices random genes super quickly; eventually it'll get it right.
civilscientist
Heh, you just described a branch of metagenomics. Bacterial "machines" are pretty nifty.
parksAndRings
Or you can pay the thousands for a company to do it for you
Pegussu
In fairness, they did splice dinosaurs with frog DNA. But on the other hand, that didn't do what they want so you have a point.
And cuttlefish, don't forget the cuttlefish.
FunPolice
Actually it did do what they wanted, that was the point of that side plot with Dr. Wu and that one war mongering raptor fanatic.
I'm talking about the original film in which the dinosaurs had one gender, but the frog DNA fucked that up.
Ah fair enough, I thought you were talking about the most recent film, my bad.
Well 1 you can. There were billions of different type of bacterial till, wow, antibiotics.
did... did you just call cancer a bacteria
cont: it's easy to say pre-penicillin that a single cure for bacterial infections would be impossible as there's so many types of bacteria
No, I'm saying we ARE in the same position with cancer as we WERE with bacteria before penicillin. That should be obvious.
Well, no. Most people think all cancer can be cured by one thing. That's like saying all creatures that walk on 4 legs are dogs (1/x)
No it's like saying all mammals will die when exposed to a certain gas, like sarin. This is not at ALL 4-legged non-dog fallacy.
(2/x) cancer comes in all kinds of variety and need different solutions for each one. Best thing we can do is try to cure every kind, but
I appreciate there are different cancers, but they have the same fundamental mechanism of pathology. More common than between all bacteria.
How could the same thing not be said about Bacteria to discourage any research into a drug like penicillin?
3/x some are just too deadly and we need more time.
You never explained how you can be so sure that a single cure for cancer is impossible. Bacteria are all so variable yet single common cure.
scabab
Cancer is PART of the animal genome. Its programmed death for when organisms are no longer reproductively useful.
http://www.theguardian.com/commentisfree/2012/nov/18/cancer-evolution-bygone-biological-age
apparently this is controversial, so im adding some references: http://www.news-medical.net/news/2007/04/17/23697.aspx
Harpdemon
What about children getting cancer? Or young adult who can reproduce?
Haha, i knew someone would ask that. Cancer doesnt have a calendar, there are always outliers. Google the statistics on cancer and age!
Bell curve, yknow?
Cancer happens when the part of the genome that causes cell death malfunctions. Cancer has never been part of the genome.
WhoTheFuckisGavin
Agreed, while cell-death is part of the genome. Tumours are malfunctions due to evolutionary possibilities (mutations). A necessary evil.
1) Actually, no. The only mutations that are important for evolution are the ones that are passed down. Cancer cells are body cells, so
2) they are not a "byproduct of evolution." They're just a rogue cell that got damaged and doesn't know when to stop growing. The harmful
4) evolutionary possibilities. Cancer is completely different.
3) side of evolution is exemplified by genetic diseases like cystic fibrosis or sickle cell anemia. Those are malfunctions due to
like thats LITERALLY it. There are a few genes that are essentially wheel chocks. When you remove them, the human genome produces cancer.
That logic doesn't make any sense. It's like saying my car is designed to crash because IF I took the brakes off it would be hard to drive.
No. Haha. Definitely no. Its like saying if i took the brakes off your car it would drive to the nearest government building and start 1/2
2/2 dissolving the walls to build a new hyper efficient car factory.
yeah... damage to the tumour suppression gene.
Damage to the TSG isn't programmed. Programmed cell-death is normal but tumours are about surviving on cellular levels, not dying.
No no, survival mechanisms are naturally selected for. Natural selection requires reproduction. Cancer does not increase the fitness 1/2
(what i mean is: tumour survival is not naturally selected for on a generational scale - organismal death is)
2/2 of the organism, so its attributes can only be selected for when viewed as altruistic genes in a broader social evolution.
Cancer as such isn't part of the animal genome but mutations are. Mutations lead to evolution but also to things like cancer.
Cancer absolutely is a part of the animal genome. You think metastasis doesnt require genetic code? Or ECM degradation? Or mesenchymal 1/2
2/2 migration? What about angiogenesis?
Sc1003
This is why cancer is so hard to treat. It is literally just regular cells that malfunction. Either they grow uncontrollably or don't die.
Yes but my point is that this malfunction itself has evolved, and through natural selection of the human genome cancer has been provided 1/2
3/? use methods of kinesis only otherwise used during embryonic development (both mesenchymal and amoeboid), it targets key organs and
2/? with essentially every trick in the book. It degrades the surrounding ECM to make room for growth, sends of individual migratory cells
4/? pathways for migration (e.g. to stabilize in the bones). Cancer aint just a biological mishap.
MostOfYouArePathetic
This is one of those times where people with no biology background think they know what they're talking about, but they don't
MimicOctopi
Honestly, I think the cure lies within ourselves. If we can find a way to increase our antibodies at a rapid rate that would be awesome.
As if cloning and hybridising is the same as fully understanding and rewriting genetic code...
Cd06771
Are u sure cuz it seems Kim Jong un found a cure ... http://www.newser.com/story/208602/kim-jong-un-claims-to-have-cured-cancer.html
HotSock
But did you know the mitochondria is the powerhouse of the cell!?
BurtMaklinFBI
Thank you so much for this
kerms
Did you know that mitochondria is the plural of mitochondrian?
Yeah, I'm working on CRISPR in a biochemistry lab right now. If DNA splicing is so easy, why I am doing so much work?
CephaloGeek
How's that going? I'm thinking of trying it in Aplysia
I feel you. I making multiple KO human cell lines at the moment. Super fun. All the subcloning...
iplaybasketball
I'm doing it in mice and I tell ya, somewhat underwhelming in terms of genetic modification. They do have funky toll like receptors now, tho
Barkinsons
"If you know the gene defects that cause cancer, why can't you just fix them?" sigh
HaliRyan
<- Layman with no biology knowledge. Why can't you?
Gene therapy is incredibly difficult to aim, both tissue and genome wise, and progressed cancer is not genetically uniform, mutating heavily
SirDoober
Another layman making a guess: Because there's a fairly big step between identifying a defect and figuring out how to un-defect it.
Sprixxen
Like finding a broken spaceship and taking it apart to fix it. You identify the part that is broken, but you still need to build a new one.
Followeer
(With my limited Knowledge of Cancer,) Basically, In order to have a chance of Getting Cancer, you need to have 2 Mutated Alleles.
After that, you have a CHANCE of getting it, and besides. Cancer is just cells reproducing uncontrollably. But its your own cells
Es27
...and literally every specialized profession, because people have opinions about a wide range of things and can only be experts in a 1/2
Few at most, but what is great is that you can talk to people and clear things up, and then they learn something new 2/2
A few weeks ago, someone had a discussion with me on the internet about epigenetics. I'm majoring in it. He wouldn't believe me. Some people
Fenderzilla
Yeah right
Gaaarrr
I don't believe you, I'm an expert on whatever that is.
nothingtodowithexplosions
I fucking love epigenetics.
TheWrathFromHighAtopTheThing
Is it real?
MainSane
I had someone on the internet try to tell me a single bacterium is 90% complex as a human being because of "chemical processes"
RookieMove
Assigning a percentage value to complexity is not exactly sensible either
khuan
I love when this happens so much. It amuses me so much.
TheBeautifulPsyche
Sooo much
So so much
notme222
Don't feel bad. If the stories are true, Charlie Chaplin once lost a Charlie Chaplin impersonation contest.
previoustopcomment
I thought it was dolly parton.
FeckItImAubreyPlazaNow
Dolly Parton lost a lookalike contest to a drag queen (iirc).
TheAnonBagpipe
I wouldn't be surprised if Dolly Parton lost a Charlie Chaplin impersonation contest...
Jonpapabear
This deserves more attention in my opinion.
as a physicist, try talking to average people about quantum mechanics.
grobbes95
Any time I even hear the words quantum mechanics, I lose 3 days of sleep so thank you, friend.
FarkasMacTavish
I like how people are confused about why observing a subatomic particle changes what it's doing because of course it does.
WE JUST SMACKED IT WITH A PHOTON OF COURSE IT IS GOING TO CHANGE ITS TRAJECTORY
ToddimusMaximus
"When you are not looking it it a wave. When you are looking it is a particle." What is changing when you look? Photons are hitting it NEway
But they're not bouncing back into our eyes, which is what we need to use in order to see it. :U
So after they bounce into our eye, they go back and tell the electron to be a particle? The information goes back in time?
worse is probably the way they misinterpret QM and use it to justify BS. No, the uncertainty principle does NOT mean psychic powers exist
But does it mean a whale can appear in the upper atmosphere and plummet to its death whilst naming things? o3o
No, but that would be awesome.
"Oh no, not again." -bowl of petunias, according to some
cupcaker
To be fair, I don't remember anyone in Jurassic Park having cancer... so maybe they did cure it.
johanevj
No. It doesn't mean that.
SnakeskinJacket
We're going to be seeing if we have the same priorities sooner than you think - https://en.m.wikipedia.org/wiki/Crispr
MonserrSans2
But the electron is being hit with a photon regardless of where the photon goes afterwards, be it an eye ball or a pile a crap.
Julios
The good stuff haha. That is why bad guys are bad.
roeloel
+1 i agree with his argument
HalfApeHalfBanana
Also its a goddamn film
Treblaine
Cancer-cure is almost the opposite of cloning. Curing cancer is getting certain cells to stop living, cloning is about making them live anew
kongfuchicken
Heh... On the fly! Get it?
PattiMichelle
But that's a useless answer, right? The actuality is that these are all inventions, so nobody has any idea what people would do there.
FlareonTheFalseProphet
In the Marvel universe Venom showed the capability to cure cancer if it bonded with the person who had it
Elerich
https://imgflip.com/i/n6zjc
bjjohnson6021
How they gonna cure cancer when they can't even think to add another tower to the island so their radios and phones work.
AClassyWalrus
BUT MOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOMMMMMMM!!! I WANNA MAKE DINOSAURS!!!!!
Digiphage
Some people take FICTION way too seriously...
CaiGwydion
They certainly can do. It's gets ridiculous sometimes. It's a movie. Oh well, some people will find something to complain about.
Stegostoma
Notice how they fuck shit up? Clearly they don't know as much as they pretend.
aestheticwolfgang
Jurassic exists inside a post-classical hollywood state, therefore it operates outside of our world within in its own bubble universe
FrankCastlePunisher
The solution to this debate would be to turn everybody who has cancer into dinosaurs...win win?
Chizbits
Pterodactyls always make me think of Beetlejuice when they change their faces to scary.
BiologyNStuff
You don't need mastery of the entire genome to clone and/or change an organism.
BiologyNStuff
Also, cancer is a way more complicated problem than just genomics.
Spanked84
Comic panel is from Spider-man and X-men if anyone cares. Issue #2 I believe.
Alicecold
I need to point out that your link is very meta.
Spanked84
My link?
Alicecold
the autolink #2
Spanked84
Ohhh lol
thisisjoey
I always wondered why they keep thinking it's a good idea. "Sure lots of people died the last 3 times, what could possibly go wrong now"
thisisjoey
I loved the movie though, just saw it tonight, it was great
Magnivore
Is that pterodactyl wearing underwear?
elandriel
read the books, it actually talks about how Hammond was really arrogant with his technology that all he really wanted to do was (1/2)
elitehunter67
I agree in the sense that he was arrogant. But most of Crichtons books have to do with abuse of power. People are douchbags. Not science.
elandriel
make money, even though he could have done a lot of scientific good with it. He was a dick. (2/2)
jetflight
This. Read a book, people.
TheresAGermanWordForThat
ToastedVanilla
Excuses excuses. Money is a way to a mean. Just ask Lex Luthor. A supervillian advertising hair growth products does sound incredible though
JamBarn
Sauron does what he wants, spider-man. Don't try to impose your values.
thatpatguy
So, uh... how often do we see people with cancer in the Jurassic Park movies?
Elerich
how often do we see dinosaurs in cancer movies?
GlitterInTheDarkNearTheTannhauserGate
None! Cancer cure made them enough money to finish the park
MartialSpork
I'm upvoting you solely because C-beams glitter in the dark near the Tannhauser Gate
GlitterInTheDarkNearTheTannhauserGate
thanks, but i am afraid in time it'll be lost, like tears in rain
ImASexyUnicorn
And why they spared no expense!
JauneArcMKII
I'm fairly sure the human genome and dino genomes aren't the same, though. I'm also not a scientist, so I know fuck all.
CaptainAmerica24
yes the genomes aren't the same, but basic DNA composition should be. If you can manipulate Dino genes, you should be able to do so with ppl
zviosif
Actually, they are EXACTLY the same. TMYK.
veritas1980
1 minute internet research indicates an estimate of 65%
ScruffyBelievesInThisCompany
I thought everyone on this site was a scientist!
veritas1980
probably a lot more similar than you think.
bananamannock
Legit geneticist here. We don't need to know a genome to clone it...
bananamannock
NB. Messing with genome in humans is illegal in most countries if ur referring to genetic mods.
nopo
When you are at the point where you can do large scale genetic engineering and splicing, the differences stop mattering as much.
cerberus63
DNA is DNA is DNA. A lot of our genetic research happens using flies and the like. Genes do the same stuff to them that it does to us.
cerberus63
That being said Jurassic Park totally uses it as a vague hand wave to explain any techno-sorcery that is happening.
JrElmoe
Nothing really related to the genomes, but more on the fact they can reconstruct the cell structures from the bottom.
Tunisia
I am a scientist and would like to state that actually, the human and tyrannosaurus genomes are identical.
Majorgrunt
well. A lot of it probably is.
MrPredator
The only thing I've learned is that rapid mutation of the human body would result in the death of the subject. On the otherhand... "science"
RhealityBytes
We would share a crazy amount of our DNA with random shit, like Bananas we share 50% of our DNA with them.
goldengoldblum
[Eugene I'm not actually a scientist gif]
whalekaraokeparty
We're all scientists here on imgur
TheGingerBeardedBiologist
They are very different. Also, being able to spice and replicate dino DNA doesn't mean we could cure diseases, especially ones like cancer.
BtchMuffin
Tell me, what kind of spice goes well with dino DNA?
longdarkteatimeofthesoul
1) But it would advance the hell out of gene therapy. The genomes are different but many of the basic mechanisms are the same. That's why we
TheGingerBeardedBiologist
I totally agree, there are many similarities too. I meant that tumblr OP is overgeneralising, and it's not as simple.
longdarkteatimeofthesoul
3) not always that simple).
longdarkteatimeofthesoul
2) can get E. coli to produce things like human insulin - the basic idea of DNA->RNA->Protein is the same in all organisms (although it's
bimpnottin
Thanks for giving a realistic view on the matter.
TheGingerBeardedBiologist
People often hate me for being a killjoy with these things. I still appreciate the humour, but also find it interesting to discuss it.
GreatWhiteSnark
You can make goats produce spider silk pretty easily so who fucking knows
vindik8or
You can make them produce the silk protein, but they can't spin it into silk.
MyxlPlyxl
Did somebody recently watch Game Theory? :3
DiplMaleNurseToBe
This is trivial, because the spider-silk genes are well known, so are the milk-producing promoters.
GreatWhiteSnark
Not really, if the knowledge is the only barrier then does it matter what is turned into dinosaurs? Recently trex cells were found
GreatWhiteSnark
Source Steve Irwin's son
DiplMaleNurseToBe
Point is that you only have to put one gene at one point in a genome to get spiders milk. A living creature needs 1000 act genes in concert.
GreatWhiteSnark
Wait. That's the problem? Not the fact that people's already well established cells and bone structure would have to be magically changed?
DiplMaleNurseToBe
No, but the knowledge and the techniques to manipulate them are identical. Making a Tyrannosaurus rex from pieces is VERY advanced gentech.
underlord2132
But it implies a level of science high enough to do some cool shit. Other than dinosaurs that is.
amglasgow
No, but JP universe clearly has genetic technology in advance of ours, so probably there is better genetic therapy for cancer.
exacerangutan
Considering how well the dinosaur-making turns out do you REALLY thing they're ready for clinical trials?
amglasgow
Their dinosaurs turned out wonderfully -- it's not the fault of the geneticists their engineers designed the parks with no safety measures.
exacerangutan
I'm just saying, you cure someone's cancer and next thing you know the cancer gets loose and starts eating people.
brotasticbrojaculation
can't fuck with that logic.
Cheesecakecrush
Maybe it IS cured in the JP universe, therefore people being eaten by dinosaurs don't give a flying fuck about cancer.
IAmDrBanner
Maybe it does, but it isn't the focal point of the movie, so really, why would they mention it at all? I don't understand the point of this.
amglasgow
I don't see any reason they would either. I was just answering the previous comment.
DarthFutuza
It would be a complete waste of screen time to have some side character be like, "Thank goodness we don't have to worry about cancer."
perpetuallylove
It's cuz we're fun at parties (in Chandler voice)
efemral
George W signed an executive order that effectively held back this kind of research for a decade.
Luciferyourgod
Link?
efemral
https://embryo.asu.edu/pages/george-w-bush-executive-order-13455-june-2007
VaclavUrbanek
Isn't one of Spider-Man's enemies literally a guy who wanted to cure himself with lizard DNA but instead mutated into a raging monster?
EmpoleonNorton
Yeah, was trying to regrow his lost arm. Curt Connors/The Lizard.
LamStock
Spidermans in the above picture.
VaclavUrbanek
Yes, that was my point. :)
DarthFutuza
The morale of the story is science is bad.
crookednixon
Basically this: http://dresdencodak.com/2009/09/22/caveman-science-fiction/
longdarkteatimeofthesoul
Sometimes I feel like lots of movies have that moral. Which is a little sad.
cegimerhange
I think the moral is more like "Don't be reckless" instead of "science is bad" in most cases.
GaryFreakinOak
The moral of the story is to never use experimental science on people, even if they volunteer. Or its you.
DarthFutuza
Stop cancer research today! It could result in zombie viruses!
SonOfTheShire
Ah, but Spider-Man also got his powers from science, and he's a good guy. Where's your moral now, Aesop?!
crookednixon
Spider-Man did not try to get spider powers, it was an accident. The Lizard tried to "play god" and it backfired.
DarthFutuza
Spider-man is a tragic hero, everyone he loves dies. His misfortune comes because of science's mistakes. Parents were murdered 4 science.
xrufus7x
But, because of science he is able to save countless lives, not only because of his powers, but also because he is a scientist himself. 1/2
xrufus7x
Seems like the true moral is "With great power comes great responsibility"
DarthFutuza
Pssshhhh don't take jokes too seriously.
nerdextreme
Well 1 you cant cure cancer. There are all types of cancer that need different cures. 2 DNA splicing isn't (relatively) that hard.
GeneticGenius
this guy
bigbrother
Different cures 120% of the time. The protein that went awry is the primary target for the 'cure'/treatment and it doesn't always work.
JamBarn
Gene therapy delivered via virus is already curing cancer and it's still early stage. Very exciting. http://killingcancer.vice.com
DoctorWatchamacallit
*treating certain types of cancer under controlled conditions. that's hugely different from a cancer miracle cure
JamBarn
Agreed, check out the documentary. I think you'll be encouraged and it's very interesting.
bimpnottin
I think one of the next stages will be altering epigenetic patterns to cure cancer. I love that field of genetics.
mybrothersmario
seriously, we can do that now, you just need to be able to fund it, and have the equipment.
nerdextreme
and have dino DNA, which is basically gone by now. But we can try doing what they did in World and use other animal dna to get close
PGTipsMonkeh
Actually, blood vessels were found in a fossil back in 2003. One of the bones broke when it was transported, they looked closer, and voila!
nerdextreme
:0
metalman125
Game theory? Game theory.
longdarkteatimeofthesoul
Doesn't mean all the DNA is intact. It's relatively stable but not millions of years stable. They can get fragments but more is unlikely.
SleepyWalrus
indeed, i read recently that they had found soft tissue in the marrow or so of a bone? maybe it's the same, but it's interesting nonetheless
PGTipsMonkeh
Maybe not, but it certainly gives me hope. Always wanted a pet triceratops
amglasgow
Splicing DNA isn't hard; splicing the right DNA to do what you want is hard.
Treblaine
Genuinely, it's easy to accidentally clone your chair as some DNA in the wood of the chair you were sitting on ended up in PCR machine.
nerdextreme
roight
GaryFreakinOak
rrrrrrrrooiiiiiiiiiiiiiiiiiiiiiiiiggggghhht...
IHateTheLetterF
We just need a machine that splices random genes super quickly; eventually it'll get it right.
civilscientist
Heh, you just described a branch of metagenomics. Bacterial "machines" are pretty nifty.
parksAndRings
Or you can pay the thousands for a company to do it for you
Pegussu
In fairness, they did splice dinosaurs with frog DNA. But on the other hand, that didn't do what they want so you have a point.
GaryFreakinOak
And cuttlefish, don't forget the cuttlefish.
FunPolice
Actually it did do what they wanted, that was the point of that side plot with Dr. Wu and that one war mongering raptor fanatic.
Pegussu
I'm talking about the original film in which the dinosaurs had one gender, but the frog DNA fucked that up.
FunPolice
Ah fair enough, I thought you were talking about the most recent film, my bad.
Treblaine
Well 1 you can. There were billions of different type of bacterial till, wow, antibiotics.
nerdextreme
did... did you just call cancer a bacteria
Treblaine
cont: it's easy to say pre-penicillin that a single cure for bacterial infections would be impossible as there's so many types of bacteria
Treblaine
No, I'm saying we ARE in the same position with cancer as we WERE with bacteria before penicillin. That should be obvious.
nerdextreme
Well, no. Most people think all cancer can be cured by one thing. That's like saying all creatures that walk on 4 legs are dogs (1/x)
Treblaine
No it's like saying all mammals will die when exposed to a certain gas, like sarin. This is not at ALL 4-legged non-dog fallacy.
nerdextreme
(2/x) cancer comes in all kinds of variety and need different solutions for each one. Best thing we can do is try to cure every kind, but
Treblaine
I appreciate there are different cancers, but they have the same fundamental mechanism of pathology. More common than between all bacteria.
Treblaine
How could the same thing not be said about Bacteria to discourage any research into a drug like penicillin?
nerdextreme
3/x some are just too deadly and we need more time.
Treblaine
You never explained how you can be so sure that a single cure for cancer is impossible. Bacteria are all so variable yet single common cure.
scabab
Cancer is PART of the animal genome. Its programmed death for when organisms are no longer reproductively useful.
scabab
http://www.theguardian.com/commentisfree/2012/nov/18/cancer-evolution-bygone-biological-age
scabab
apparently this is controversial, so im adding some references: http://www.news-medical.net/news/2007/04/17/23697.aspx
Harpdemon
What about children getting cancer? Or young adult who can reproduce?
scabab
Haha, i knew someone would ask that. Cancer doesnt have a calendar, there are always outliers. Google the statistics on cancer and age!
scabab
Bell curve, yknow?
longdarkteatimeofthesoul
Cancer happens when the part of the genome that causes cell death malfunctions. Cancer has never been part of the genome.
WhoTheFuckisGavin
Agreed, while cell-death is part of the genome. Tumours are malfunctions due to evolutionary possibilities (mutations). A necessary evil.
longdarkteatimeofthesoul
1) Actually, no. The only mutations that are important for evolution are the ones that are passed down. Cancer cells are body cells, so
longdarkteatimeofthesoul
2) they are not a "byproduct of evolution." They're just a rogue cell that got damaged and doesn't know when to stop growing. The harmful
longdarkteatimeofthesoul
4) evolutionary possibilities. Cancer is completely different.
longdarkteatimeofthesoul
3) side of evolution is exemplified by genetic diseases like cystic fibrosis or sickle cell anemia. Those are malfunctions due to
scabab
like thats LITERALLY it. There are a few genes that are essentially wheel chocks. When you remove them, the human genome produces cancer.
longdarkteatimeofthesoul
That logic doesn't make any sense. It's like saying my car is designed to crash because IF I took the brakes off it would be hard to drive.
scabab
No. Haha. Definitely no. Its like saying if i took the brakes off your car it would drive to the nearest government building and start 1/2
scabab
2/2 dissolving the walls to build a new hyper efficient car factory.
scabab
yeah... damage to the tumour suppression gene.
WhoTheFuckisGavin
Damage to the TSG isn't programmed. Programmed cell-death is normal but tumours are about surviving on cellular levels, not dying.
scabab
No no, survival mechanisms are naturally selected for. Natural selection requires reproduction. Cancer does not increase the fitness 1/2
scabab
(what i mean is: tumour survival is not naturally selected for on a generational scale - organismal death is)
scabab
2/2 of the organism, so its attributes can only be selected for when viewed as altruistic genes in a broader social evolution.
WhoTheFuckisGavin
Cancer as such isn't part of the animal genome but mutations are. Mutations lead to evolution but also to things like cancer.
scabab
Cancer absolutely is a part of the animal genome. You think metastasis doesnt require genetic code? Or ECM degradation? Or mesenchymal 1/2
scabab
2/2 migration? What about angiogenesis?
Sc1003
This is why cancer is so hard to treat. It is literally just regular cells that malfunction. Either they grow uncontrollably or don't die.
scabab
Yes but my point is that this malfunction itself has evolved, and through natural selection of the human genome cancer has been provided 1/2
scabab
3/? use methods of kinesis only otherwise used during embryonic development (both mesenchymal and amoeboid), it targets key organs and
scabab
2/? with essentially every trick in the book. It degrades the surrounding ECM to make room for growth, sends of individual migratory cells
scabab
4/? pathways for migration (e.g. to stabilize in the bones). Cancer aint just a biological mishap.
MostOfYouArePathetic
This is one of those times where people with no biology background think they know what they're talking about, but they don't
MimicOctopi
Honestly, I think the cure lies within ourselves. If we can find a way to increase our antibodies at a rapid rate that would be awesome.
scabab
As if cloning and hybridising is the same as fully understanding and rewriting genetic code...
Cd06771
Are u sure cuz it seems Kim Jong un found a cure ... http://www.newser.com/story/208602/kim-jong-un-claims-to-have-cured-cancer.html
HotSock
But did you know the mitochondria is the powerhouse of the cell!?
BurtMaklinFBI
Thank you so much for this
kerms
Did you know that mitochondria is the plural of mitochondrian?
longdarkteatimeofthesoul
Yeah, I'm working on CRISPR in a biochemistry lab right now. If DNA splicing is so easy, why I am doing so much work?
CephaloGeek
How's that going? I'm thinking of trying it in Aplysia
civilscientist
I feel you. I making multiple KO human cell lines at the moment. Super fun. All the subcloning...
iplaybasketball
I'm doing it in mice and I tell ya, somewhat underwhelming in terms of genetic modification. They do have funky toll like receptors now, tho
Barkinsons
"If you know the gene defects that cause cancer, why can't you just fix them?" sigh
HaliRyan
<- Layman with no biology knowledge. Why can't you?
Barkinsons
Gene therapy is incredibly difficult to aim, both tissue and genome wise, and progressed cancer is not genetically uniform, mutating heavily
SirDoober
Another layman making a guess: Because there's a fairly big step between identifying a defect and figuring out how to un-defect it.
Sprixxen
Like finding a broken spaceship and taking it apart to fix it. You identify the part that is broken, but you still need to build a new one.
Followeer
(With my limited Knowledge of Cancer,) Basically, In order to have a chance of Getting Cancer, you need to have 2 Mutated Alleles.
Followeer
After that, you have a CHANCE of getting it, and besides. Cancer is just cells reproducing uncontrollably. But its your own cells
Es27
...and literally every specialized profession, because people have opinions about a wide range of things and can only be experts in a 1/2
Es27
Few at most, but what is great is that you can talk to people and clear things up, and then they learn something new 2/2
bimpnottin
A few weeks ago, someone had a discussion with me on the internet about epigenetics. I'm majoring in it. He wouldn't believe me. Some people
Fenderzilla
Yeah right
Gaaarrr
I don't believe you, I'm an expert on whatever that is.
nothingtodowithexplosions
I fucking love epigenetics.
TheWrathFromHighAtopTheThing
Is it real?
MainSane
I had someone on the internet try to tell me a single bacterium is 90% complex as a human being because of "chemical processes"
RookieMove
Assigning a percentage value to complexity is not exactly sensible either
khuan
I love when this happens so much. It amuses me so much.
TheBeautifulPsyche
Sooo much
MyxlPlyxl
So so much
notme222
Don't feel bad. If the stories are true, Charlie Chaplin once lost a Charlie Chaplin impersonation contest.
previoustopcomment
I thought it was dolly parton.
FeckItImAubreyPlazaNow
Dolly Parton lost a lookalike contest to a drag queen (iirc).
TheAnonBagpipe
I wouldn't be surprised if Dolly Parton lost a Charlie Chaplin impersonation contest...
Jonpapabear
This deserves more attention in my opinion.
DoctorWatchamacallit
as a physicist, try talking to average people about quantum mechanics.
grobbes95
Any time I even hear the words quantum mechanics, I lose 3 days of sleep so thank you, friend.
FarkasMacTavish
I like how people are confused about why observing a subatomic particle changes what it's doing because of course it does.
FarkasMacTavish
WE JUST SMACKED IT WITH A PHOTON OF COURSE IT IS GOING TO CHANGE ITS TRAJECTORY
ToddimusMaximus
"When you are not looking it it a wave. When you are looking it is a particle." What is changing when you look? Photons are hitting it NEway
FarkasMacTavish
But they're not bouncing back into our eyes, which is what we need to use in order to see it. :U
ToddimusMaximus
So after they bounce into our eye, they go back and tell the electron to be a particle? The information goes back in time?
DoctorWatchamacallit
worse is probably the way they misinterpret QM and use it to justify BS. No, the uncertainty principle does NOT mean psychic powers exist
FarkasMacTavish
But does it mean a whale can appear in the upper atmosphere and plummet to its death whilst naming things? o3o
DoctorWatchamacallit
No, but that would be awesome.
BurtMaklinFBI
"Oh no, not again." -bowl of petunias, according to some